Wednesday, February 22, 2012

For example, penicillin affect the enzymes...

SURFACE LAYERS Bacteria have several different surface layers, which can improve their pathogenicity. These layers are listed below:


Capsules: This type of surface layer is the main high molecular weight polysaccharides. If the layer is strongly bound to the cell wall is called the capsule, and if not, he called a slime layer. These layers provide resistance to phagocytosis and serve as antigenic determinants. Production of capsules and genetically fenotypno control. Cell wall: cell wall is the basis for the classification of bacteria per gram. Gram-positive bacteria a thick layer of peptidoglycan external to the cytoplasmic membrane. Unlike Gram-negative bacteria have a thin peptidoglycan layer located between the cytoplasmic membrane and the second membrane called the outer membrane. This region is known as periplazmaticheskoho space. Other important components of the cell wall include the following:


peptidoglycan: This is a polymer of alternating N-atsetilmuramovoy acid (NAM) and N-acetylglucosamine (Nag). Long strings of alternating polymer can be related to L-alanine, D-glutamic acid, L-lysine, D-alanine tetrapeptidov in DL (


pneumonia auscultation sounds

). Gram-positive cells have a much higher cross-linked peptidoglycan structure than Gram-negative cells. Peptidoglycan and the target of antimicrobial activity. For example, penicillin affect the enzymes involved in peptidoglycan biosynthesis while physically split the lysozyme-NAG until the bonds. Lipoteyhoevaya acid lipoteyhoevaya acid (LTA) are found only in gram-positive bacteria. These polysaccharides continue even though all the peptidoglycan layer and appear on the cell surface. As a result, these structures may serve as antigenic determinants. Lipopolysaccharide: lipopolysaccharide (LPS) are found only in gram-negative bacteria. These structures consist of a lipid that binds LPS in the strattera side effects outer membrane itself endotoksychnoho part of the molecule. Polysaccharide fragment appears on the cell surface, serving as antigenic determinants (O antigen). .

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